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Latest News By Stage


A

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Acute Lymphoblastic Leukemia

FDA Approves Mylotarg for Treatment of Acute Myeloid Leukemia (September 5, 2017)

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML). The FDA also approved Mylotarg for... Continue Reading

FDA Approves First Gene Therapy (September 1, 2017)

CAR T-cell therapy approved to treat certain children and young adults with B-cell acute lymphoblastic leukemia The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering... Continue Reading

FDA Approves First Gene Therapy (September 1, 2017)

CAR T-cell therapy approved to treat certain children and young adults with B-cell acute lymphoblastic leukemia The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering... Continue Reading

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Acute Myeloid Leukemia

Gilteritinib Approved for Advanced Acute Myeloid Leukemia (AML) with a FLT3 Mutation (November 29, 2018)

The U.S. Food and Drug Administration approved Xospata (gilteritinib) for treatment of adult patients who have recurrent or refractory acute myeloid leukemia (AML) with a FLT3 mutation. About Xospata Xospata has demonstrated inhibitory activity against... Continue Reading

FDA Approves Venclexta Combination for AML in Adults (November 26, 2018)

The Food and Drug Administration granted accelerated approval to Venclexta (venetoclax) in combination with azacitidine or decitabine or low-dose cytarabine for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are age 75 years... Continue Reading

Tibsovo Approved for Treatment of Relapsed/Refractory Acute Myeloid Leukemia and an IGH1 Mutation (July 23, 2018)

Tibsovo® (ivosidenib) has been granted approval from the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (R/R AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation... Continue Reading

U.S. FDA Approves Trisenox® Injection for First Line Treatment of Acute Promyelocytic Leukemia (January 31, 2018)

CancerConnect News: the U.S. Food and Drug Administration (FDA) has approved the use of Trisenox® (arsenic trioxide) injection in combination with tretinoin for the treatment of adults with newly-diagnosed low-risk acute promyelocytic leukemia (APL)... Continue Reading

FDA Approves Mylotarg for Treatment of Acute Myeloid Leukemia (September 5, 2017)

The U.S. Food and Drug Administration today approved Mylotarg (gemtuzumab ozogamicin) for the treatment of adults with newly diagnosed acute myeloid leukemia whose tumors express the CD33 antigen (CD33-positive AML). The FDA also approved Mylotarg for... Continue Reading

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Acute Promyelocytic Leukemia

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Adjuvant (I-III, A-C) Colon Cancer

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Adult Acute Lymphoblastic Leukemia

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Advanced Stage Hodgkin's Lymphoma

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Advisory Complementary Alternative Medicine

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Aggressive/Intermediate Grade Non-Hodgkin's Lymphoma

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All Cancer Types

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Allogeneic Stem Cell Transplant

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Alphabetical Sort

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Alternative Medical Systems Complementary Alternative Medicine

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Anal Cancer

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Autologous Stem Cell Transplant

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B

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Barrett's Esophagus Esophageal Cancer

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Biologic-Orthomolecular Therapies Complementary Alternative Medicine

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Biological Therapy

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Bladder Cancer

FDA grants accelerated approval to erdafitinib for metastatic urothelial carcinoma (April 16, 2019)

granted accelerated approval to Balversa (erdafitinib) for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing chemotherapy,... Continue Reading

Vicinium Represents New Treatment Option for Non- Muscle Invasive Badder Cancer (June 6, 2018)

Today three-month data from the ongoing Phase 3 VISTA Trial of Vicinium for the treatment of patients with high-grade non-muscle invasive bladder cancer (NMIBC) who have been previously treated with bacillus Calmette-Guérin (BCG) were released. Overall... Continue Reading

U.S. FDA Grants Fast Track Designation to GemRIS™ in Muscle Invasive Bladder Cancer (May 4, 2018)

CancerConnect News: The United States Food and Drug Administration (FDA) has granted Fast Track designation for GemRIS (TAR-200) for the treatment of patients with organ-confined or locally-advanced Muscle Invasive Bladder Cancer who are unfit for curative... Continue Reading

Breakthrough Therapy Designation Awarded for Enfortumab Vedotin in Locally Advanced or Metastatic Bladder Cancer (April 3, 2018)

CancerConnect News: The U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to enfortumab vedotin for patients with locally advanced or metastatic urothelial (bladder) cancer who were previously treated with checkpoint... Continue Reading

Keytruda Improves Survival of Advanced Bladder Cancer (February 26, 2018)

CancerConnect News: Patients with recurrent urothelial cancer lived longer when they received Keytruda (pembrolizumab) compared to chemotherapy as second-line treatment, according to long-term follow of a clinical trial presented at the Genitourinary... Continue Reading

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Bone Cancer

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Brain Cancer

First In Class Immunostimulating Anticancer Agent able to Directly Inhibit Tumor Signaling and Kill Tumor Cells, is in Clinical Trial for Glioblastoma and Melanoma Metastatic to the Brain (September 13, 2018)

Small molecule lead drug candidate blocks a critical target for tumors and crosses the blood brain barrier; begins first brain cancer patient dosing in clinical trial at MD Anderson Cancer Center HOUSTON, TX – September 13, 2018 – In the ongoing... Continue Reading

Engineering the Common Cold Virus Appears to be Promising Treatment Approach for Some Brain Tumors (July 6, 2018)

A “smart bomb” oncolytic adenovirus appears to induce dramatic responses with long-term survival in recurrent high-grade gliomas, according to the early results of a study published in The Journal of Clinical Oncology. Glioblastoma is the... Continue Reading

Interim Survival Data from Phase 3 Trial of DCVax®-L for Glioblastoma Reported (May 30, 2018)

Northwest Biotherapeutics, developer of DCVax® personalized immune therapies for solid tumor cancers, announced today the publication of interim blinded survival data from its Phase 3 clinical trial of DCVax®-L for newly diagnosed Glioblastoma brain... Continue Reading

Interim Results from Clinical Trial of Immunotherapy for Glioblastoma Show Significant Clinical Benefit (May 29, 2018)

The research team behind an emerging immunotherapy for cancer will present interim findings from an ongoing clinical study in patients with brain cancer at a major research meeting next month. Collaborators from organizations including Roswell Park Comprehensive... Continue Reading

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Breast Cancer

Piqray® approved for the treatment of postmenopausal women with breast cancer (May 29, 2019)

The US Food and Drug Administration (FDA) has approved Piqray® (alpelisib, formerly BYL719) in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor positive, human epidermal growth factor receptor-2... Continue Reading

Subcutaneous Herceptin Effective Option for Women With HER2-positive Breast Cancer (May 6, 2019)

One year of IV Herceptin (trastuzumab) is the standard of care for women with HER2-positive early stage breast cancer (ESBC). Doctors from Germany have confirmed that Herceptin can safely be administered subcutaneously without compromising effectiveness... Continue Reading

37,000 Patient Meta-Analyses Confirms Benefit of Dose Dense Therapy for Treatment of Early Stage Breast Cancer (April 30, 2019)

According to the National Cancer Institute the overall results of studies designed to compare dose dense therapy to every 3 week therapy support the use of dose-dense chemotherapy for the treatment of women with HER2-negative early stage breast cancer... Continue Reading

Dose Intense Chemotherapy Improves Survival When Used For Treatment of Early Stage Breast Cancer (April 8, 2019)

Giving chemotherapy drugs every two weeks instead of every three weeks reduces the risk of breast cancer recurrence and death in women undergoing adjuvant chemotherapy for early stage breast cancer. The analyses was performed by British physicians in... Continue Reading

Immunotherapy Offers New Hope in Triple Negative Breast Cancer (December 28, 2018)

Results from the Impassion 130 clinical trial published in the New England Journal of Medicine have demonstrated that immunotherapy can improve survival in breast cancer, especially in anti-programmed cell death ligand 1 (PD-1+) patients.  The results... Continue Reading

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C

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Cancer Dictionary

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Carcinoma In Situ Breast cancer

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Cervical Cancer

FDA Approves Merck’s Keytruda® for Previously Treated Patients with Recurrent or Metastatic Cervical Cancer Whose Tumors Express PD-L1 (June 18, 2018)

The U.S. Food and Drug Administration (FDA) has approved Keytruda (pembrolizumab) for the treatment of patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy whose tumors express PD-L1.  Keytruda is the... Continue Reading

Questions to Ask Before Radiation Therapy for the Treatment of Cervical Cancer (December 13, 2017)

Radiation therapy, or radiotherapy, is a common way to treat cervical cancer. Doctors who specialize in treating cancers with radiation are known as radiation oncologists. During radiation therapy, high-energy x-rays are used to kill cancer cells. Radiation... Continue Reading

Managment of the Side Effects of Radiation for Cervical Cancer (December 7, 2017)

Radiation therapy, or radiotherapy, is a common way to treat cervical cancer. With any treatment of cancer you must first understand your responsibility and your medical team’s role as well as explore treatment options and get a second opinion(s) before... Continue Reading

What You Should Know About the Side Effects of Surgery for Cervical Cancer (December 6, 2017)

A hysterectomy is a common surgical treatment of early stage cancer and precancerous disease of the cervix in women. With any treatment of cancer it is important to first understand your responsibility and your medical team’s role as well as explore... Continue Reading

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Chemotherapy

mFOLFIRINOX Found Superior to Gemzar for Treatment Surgically Resected Pancreatic Cancer (June 19, 2018)

The results of a recently presented clinical study at the American Society of Clinical Oncology meetings last week suggest that more aggressive chemotherapy treatment improves outcomes compared to single agent Gemzar (gemcitabine) chemotherapy which has... Continue Reading

Head and Neck Cancer Patients at Risk of Cognitive Problems Following Treatment (January 8, 2018)

CancerConnect News: Patients who survive head and neck cancer may be more likely to experience declines in mental function according to the results of a recent study. The findings are drawn from cognitive assessments for 80 survivors of head and neck... Continue Reading

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Childhood Acute Lymphoblastic Leukemia

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Chronic Lymphoblastic Leukemia

Calquence Improves Survival in Relapsed Chronic Lymphocytic Leukemia (May 20, 2019)

An interim analyses of the phase 3 “ASCEND” clinical trial evaluating single-agent Calquence (acalabrutinib) compared to Rituxan (rituximab) plus idelasib or bendamustine in recurrent chronic lymphocytic leukemia (CLL) is closed early due to favorable... Continue Reading

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Chronic Lymphocytic Leukemia

duvelisib (COPIKTRA, Verastem, Inc.) for adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) (September 25, 2018)

The Food and Drug Administration granted regular approval to duvelisib (COPIKTRA, Verastem, Inc.) for adult patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) after at least two prior therapies. In... Continue Reading

FDA Approves Venetoclax for Chronic and Small Lymphocytic Leukemia/Lymphoma With or Without 17 p Deletion, (June 25, 2018)

The Food and Drug Administration granted regular approval to Venclexta (venetoclax) for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one prior therapy. Approval... Continue Reading

Venclexta Significantly Reduces Cancer Progression in Chronic Lymphocytic Leukemia (March 22, 2018)

CancerConnect News: Venclexta (venetoclax) plus Rituxan (rituximab) significantly reduces the risk of cancer progression or death at two years, compared with Treanda (bendustamine) plus Rituxan in the treatment of chronic lymphocytic leukemia that has... Continue Reading

Duvelisib; Promising New Treatment Option for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (September 11, 2017)

Results of the Phase 3 DUO study evaluating duvelisib in patients with relapsed or refractory chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) have been reported and appear very promising.  Although the treatment of CLL/SLL has advanced... Continue Reading

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Chronic Myeloid Leukemia

FDA Grants Accelerated Approval to Bosulif for Treatment of Newly-Diagnosed Chronic Myelogenous Leukemia (January 14, 2018)

CancerConnect News: On December 19, 2017, the Food and Drug Administration granted accelerated approval to bosutinib Bosulif (bosutinib) for treatment of patients with newly-diagnosed chronic phase (CP) Philadelphia chromosome positive (Ph+) chronic myelogenous... Continue Reading

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Clinical Trials Database

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Colon Cancer

ASCO Guideline: Oxaliplatin Adjuvant Therapy for Stage III Colon Cancer May Be Reduced in Select Patients (May 1, 2019)

The American Society of Clinical Oncology (ASCO) has released a new guideline that states that patients with clinically low-risk stage III colon cancer should have the option of receiving 3 months of adjuvant oxaliplatin-based chemotherapy. For patients... Continue Reading

Many Early Onset Colon Cancers are Caused by Genetic Mutations Passed Through Families (April 25, 2018)

CancerConnect News: One in every six colorectal cancer patients (16 percent) diagnosed under age 50 has at least one inherited genetic mutation that increases his or her cancer risk and many of these mutations could go undetected with the current screening... Continue Reading

Managing Side Effects From EGFR Inhibitors (April 10, 2018)

CancerConnect News: Epidermal Growth Factor Receptor (EGFR) inhibitor drugs are a type of precision cancer medicine commonly used to treat lung, colon, head and neck and other cancers that over express the EGFR.  There are several EGFR inhibitor drugs... Continue Reading

Diagnosed with Colon Cancer: 10 Tips on How to Get The Most From Your Doctor (February 21, 2018)

1) Choose Your Doctor Carefully Medical oncologists are the primary doctors involved with colon cancer and work in collaboration with surgeons and gastroenterologists. Pick a medical oncologist carefully, rely on people you trust including nurses and... Continue Reading

Ulixertinib A First-in-class ERK Inhibitor Shows Early Efficacy in Patients With Advanced Cancers (January 8, 2018)

CancerConnect News: The novel ERK1/2 kinase inhibitor ulixertinib displayed an acceptable safety profile and had clinical activity in patients whose cancers had mutations in the MAPK cell-signaling pathway, according to data from a recent phase 1 clinical... Continue Reading

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Complementary Alternative Medicine

Acupuncture Reduces Aromatase Inhibitor Joint Pain in Women with Breast Cancer (December 14, 2017)

According to a well designed study presented at the 2017 San Antonio Breast Cancer Symposium acupuncture is effective in reducing pain and stiffness associated with aromatase inhibitor (AI) therapy in women with early-stage breast cancer.1 Stiffness and... Continue Reading

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Corticosteroid

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D

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Drug Dictionary

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E

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Early Stage Hodgkin's Lymphoma

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Early Stage I-II (A-B) Prostate Cancer

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Esophageal Cancer

Keytruda Promising in PD-L1 Esophageal Cancer (February 13, 2018)

CancerConnect News: The checkpoint inhibitor Keytruda (pembrolizumab) has been reported to produce an overall response rate of 30% in patients with PD-L1–positive, advanced esophageal cancer.1 About Keytruda Keytruda is a monoclonal antibody that helps... Continue Reading

Diagnosed with Esophageal Cancer: 10 Tips on How to Get The Most From Your Doctor (December 1, 2017)

1) Choose Your Doctor Carefully Surgeons, medical oncologists and radiation oncologists are the primary doctors involved with esophageal cancer and often work in collaboration. Pick your primary oncologist carefully, rely on people you trust including... Continue Reading

New Standard of Care for Treatment of Resectable Gastric Cancer (October 3, 2017)

The superiority of docetaxel based triplet therapy over standard care in patients with resectable esophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.1 Survival in resectable... Continue Reading

The US Food and Drug Administration has Expanded the Approval of the Precision Cancer Medicine Keytruda for Treatment of Gastric Cancer (September 25, 2017)

Keytruda (Pembrolizumab) is now indicated for patients with recurrent locally advanced or metastatic gastric or gastro-esophogeal junction adenocarcinoma. Patients eligible for keytruda therapy under this new indication must have PD-L1-expressing tumors,... Continue Reading

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Ewing's Sarcoma Overview

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Extensive Lung Cancer - Small Cell

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F

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Follicular Lymphoma

FDA Approves Aliqopa for Treatment of Adults with Relapsed Follicular Lymphoma (October 18, 2017)

The U.S. Food and Drug Administration today granted accelerated approval to Aliqopa (copanlisib) for the treatment of adults with relapsed follicular lymphoma who have received at least two prior treatments known as systemic therapies. “For patients... Continue Reading

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G

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Gastric Cancer

Immunotherapy comparable to chemo for some advanced stomach cancers (June 4, 2019)

An immunotherapy drug could prove just as effective as chemotherapy in prolonging the lives of patients with advanced cancers of the stomach or food pipe. For some, the immune-boosting treatment offered improved survival compared to standard treatment. The... Continue Reading

FDA Approves Lonsurf® for Treatment of Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (March 8, 2019)

The United States Food and Drug Administration (FDA) has approved Lonsurf® (trifluridine/tipiracil)) as a treatment for adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines... Continue Reading

Diagnosed with Gastric Cancer: 10 Tips on How to Get The Most From Your Doctor (December 21, 2017)

1) Choose Your Doctor Carefully Surgeons, medical oncologists and radiation oncologists are the primary doctors involved with gastric cancer and often work in collaboration. Pick your primary oncologist carefully, rely on people you trust including nurses... Continue Reading

New Standard of Care for Treatment of Resectable Gastric Cancer (October 3, 2017)

The superiority of docetaxel based triplet therapy over standard care in patients with resectable esophago-gastric cancer has been confirmed in late-breaking results from the FLOT4 trial presented at the ESMO 2017 Congress in Madrid.1 Survival in resectable... Continue Reading

The US Food and Drug Administration has Expanded the Approval of the Precision Cancer Medicine Keytruda for Treatment of Gastric Cancer (September 25, 2017)

Keytruda (Pembrolizumab) is now indicated for patients with recurrent locally advanced or metastatic gastric or gastro-esophogeal junction adenocarcinoma. Patients eligible for keytruda therapy under this new indication must have PD-L1-expressing tumors,... Continue Reading

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Gene Therapy

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General

Tissue “Agnostic” Genomic Based Treatment With Vitrakvi and Keytruda – A Paradigm Shift in Cancer Treatment (November 28, 2018)

The US Food and Drug Administration (FDA) on Monday approved a new precision cancer medicine Vitrakvi (larotrectinib) for the treatment of adult and pediatric solid tumors that have a targetable biomarker known as a neurotrophic receptor tyrosine kinase... Continue Reading

Patients with rare, incurable digestive tract cancers respond to new drug combination (November 19, 2018)

Dublin, Ireland: Patients with rare, but incurable cancers of the digestive tract have responded well to a combination of two drugs that block the MEK and BRAF pathways, which drive the disease in some cases. They have survived for longer without the... Continue Reading

New Treatment Approved for Influenza (October 26, 2018)

The Food and Drug Administration (FDA) has approved Xofluza (baloxavir marboxil) for the treatment of acute uncomplicated influenza in patients aged ≥12 years old who have been symptomatic for no more than 48 hours. Xofluza is a first-in-class, single-dose... Continue Reading

AbbVie Announces IMBRUVICA® (ibrutinib) Plus Rituximab Approval by U.S. FDA as First Chemotherapy-Free Combination Treatment in Adults with Waldenström’s Macroglobulinemia, a Rare Type of Blood Cancer (September 4, 2018)

PRESS RELEASE PR Newswire Aug. 27, 2018, 07:00 AM NORTH CHICAGO, Ill., Aug. 27, 2018 /PRNewswire/ — AbbVie (NYSE: ABBV), a research-based global biopharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) approved... Continue Reading

FDA Approves Iobenguane I 131 (Azedra) for Rare Neuroendocrine Tumors (August 2, 2018)

The US Food and Drug Administration (FDA) today approved Azedra (iobenguane I 131) for the treatment of pheochromocytoma or paraganglioma, which are rare neuroendocrine tumors of the adrenal gland and other tissue areas. About Pheochromocytoma and Paraganglioma Pheochromocytomas... Continue Reading

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General Bone Cancer

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General Brain Cancer

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General Complementary Alternative Medicine

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General Gene Therapy

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General Head and Neck Cancer

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General HIV Related Cancers

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General Lung Cancer

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General Malignant Mesothelioma

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General Myelodysplastic Syndrome

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General Neuroblastoma

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General Renal Cancer

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General Retinoblastoma

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General Sarcoma

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General Skin Cancer

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General Thyroid Cancer

Pass it On: It’s National Thyroid Awareness Month (September 8, 2017)

The thyroid gland is a butterfly-shaped organ that is below the Adam’s apple in the front part of the neck. It produces, stores, and releases hormones that regulate vital body functions. Thyroid cancer happens when cells in the thyroid grow out of control.... Continue Reading

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General Vaginal Cancer

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H

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Hairy Cell Leukemia

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Head and Neck Cancer

FDA Approves Keytruda for First-line Treatment of Head and Neck Squamous Cell Carcinoma (June 13, 2019)

FDA approves Keytruda for the first-line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC). Keytruda was approved for use in combination with platinum and fluorouracil (FU) for all patients and... Continue Reading

Nimotuzumab in Combination With Concurrent Radiotherapy and Cisplatin Is Active in Locally Advanced SCCHN (July 19, 2018)

Nimotuzumab in combination with concurrent radiotherapy and cisplatin provides significant clinical benefits in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). About Head and Neck Cancer Head and neck cancers include... Continue Reading

University of Colorado Study Suggests new Combination Treatment for Head and Neck Cancer (June 14, 2018)

The five-year survival rate for locally-advanced head and neck cancer is only 46 percent, even with treatments including surgery, radiation, chemotherapy and/or genetically targeted treatments such as cetuximab. Often, the problem is that while treatments... Continue Reading

Managing Side Effects From EGFR Inhibitors (April 10, 2018)

CancerConnect News: Epidermal Growth Factor Receptor (EGFR) inhibitor drugs are a type of precision cancer medicine commonly used to treat lung, colon, head and neck and other cancers that over express the EGFR.  There are several EGFR inhibitor drugs... Continue Reading

Spring into Action For Oral, Head, and Neck Cancer Awareness Week! (April 3, 2018)

CancerConnect News: As the month of April brings head and neck cancer into focus, it’s time to increase public understanding of the disease, including its prevalence, approaches to screening and prevention, treatment options, and resources that offer... Continue Reading

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Health and Wellness

Understanding Low Back Pain (December 1, 2017)

From theSpineCommunity Back pain is a symptom associated with over 60 different medical conditions.  These disorders involve a number of different organ systems.  A variety of healthcare professionals have expertise that can be useful in the diagnosis... Continue Reading

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Hepatocellular Carcinoma Liver Cancer

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Highly Aggressive/High Grade Non-Hodgkin's Lymphoma

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HIV Related Cancers

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Hodgkin's Lymphoma

FDA Approves Chemoimmunotherapy Regimen for Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma (June 11, 2019)

The U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy Treanda (bendamustine) and Rituxan (rituximab) product (a combination known as “BR”), to treat adult... Continue Reading

Clinical Trial Shows Best Outcomes to Date for Older Hodgkin Lymphoma Patients (September 18, 2018)

Recently published results of a phase 2 clinical trial have shown the best outcomes to date for newly diagnosed older Hodgkin lymphoma patients treated with brentuximab vedotin given before and after doxorubicin, vinblastine and dacarbazine (AVD) chemotherapy,... Continue Reading

FDA Approves Adcetris® in Combination with Chemotherapy for Previously Untreated Stage III or IV Classical Hodgkin Lymphoma (March 22, 2018)

CancerConnect News: The U.S. Food and Drug Administration (FDA) has approved Adcetris (brentuximab vedotin) in combination with chemotherapy in adult patients with previously untreated Stage III or IV classical Hodgkin lymphoma. The approval is based... Continue Reading

Addition of the Precision Cancer Medicine Adcetris Reduces the Risk of Treatment Failure in Advanced Hodgkin Lymphoma (March 1, 2018)

CancerConnect News: Patients with advanced Hodgkin lymphoma (HL) who were treated with a multi-drug regimen that included the precision cancer medicine Adcetris (brentuximab vedotin) had a 23-percent reduction in the risk of disease progression, death,... Continue Reading

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Hormonal Therapy

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I

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Indolent/Low Grade Non-Hodgkin's Lymphoma

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Inflammatory Breast Cancer

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Info Type

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J

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K

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L

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Leukemia

Calquence Improves Survival in Relapsed Chronic Lymphocytic Leukemia (May 20, 2019)

An interim analyses of the phase 3 “ASCEND” clinical trial evaluating single-agent Calquence (acalabrutinib) compared to Rituxan (rituximab) plus idelasib or bendamustine in recurrent chronic lymphocytic leukemia (CLL) is closed early due to favorable... Continue Reading

FDA approves ivosidenib as first-line treatment for AML with IDH1 mutation (May 7, 2019)

On May 2, 2019, the Food and Drug Administration approved ivosidenib (TIBSOVO, Agios Pharmaceuticals, Inc.) for newly-diagnosed acute myeloid leukemia (AML) with a susceptible IDH1 mutation, as detected by an FDA-approved test, in patients who are at... Continue Reading

Non-Chemotherapy Combo Approved for Treatment-Naïve CLL/SLL Patients (March 11, 2019)

The U.S. Food and Drug Administration (FDA) has approved IMBRUVICA® (ibrutinib) in combination with Gazyva (obinutuzumab) for treatments of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). 1 The FDA approval was based... Continue Reading

Gilteritinib Approved for Advanced Acute Myeloid Leukemia (AML) with a FLT3 Mutation (November 29, 2018)

The U.S. Food and Drug Administration approved Xospata (gilteritinib) for treatment of adult patients who have recurrent or refractory acute myeloid leukemia (AML) with a FLT3 mutation. About Xospata Xospata has demonstrated inhibitory activity against... Continue Reading

FDA Approves Venclexta Combination for AML in Adults (November 26, 2018)

The Food and Drug Administration granted accelerated approval to Venclexta (venetoclax) in combination with azacitidine or decitabine or low-dose cytarabine for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are age 75 years... Continue Reading

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Limited Disease Lung Cancer - Small Cell

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Liver Cancer

Keytruda Immunotherapy for Treatment of Liver Cancer (November 13, 2018)

According to the results of a study presented at the recent gastrointestinal cancer symposia, Keytruda (pembrolizumab) is an active treatment for advanced liver cancer in patients who have already been treated with Nexavar (sorafenib), (1) and has not... Continue Reading

FDA Approves Lenvatinib for Treatment of Advanced Hepatocellular Cancer (August 20, 2018)

The U.S. Food and Drug Administration (FDA) approved the kinase inhibitor LENVIMA® (lenvatinib) for the first-line treatment of patients with unresectable hepatocellular carcinoma (HCC). This approval was based on results from REFLECT, where LENVIMA... Continue Reading

Cyramza Improves Survival in Poor-Prognosis Liver Cancer (July 12, 2018)

Andrew X. Zhu, MD, PhD, director of Liver Cancer Research at Massachusetts General Hospital presented new data at the 2018 World Congress on Gastrointestinal Cancer (WCGC) demonstrating that Cyramza (ramucirumab) significantly improves survival in a subset... Continue Reading

Cabometyx™ May Be ‘New Treatment Option’ for Liver Cancer (February 20, 2018)

CancerConnect News:  Treatment with Cabometyx  (cabozantinib) significantly improved outcomes in patients with advanced hepatocellular carcinoma (HCC), leading researchers to suggest that it could offer a new treatment option for this patient population. ... Continue Reading

Keytruda Immunotherapy Appears Active for Treatment of Liver Cancer (February 15, 2018)

CancerConnect News:  According to the results of a study presented at the recent gastrointestinal cancer symposia, Keytruda (pembrolizumab) is an active treatment for advanced liver cancer in patients who have already been treated with Nexavar (sorafenib).1 About... Continue Reading

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Locally Advanced Stage III (C) Prostate Cancer

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Lung Cancer

Lorbrena Approved for second- or third-line treatment of ALK-positive metastatic NSCLC (November 8, 2018)

The US Food and Drug Administration granted accelerated approval to Lorbrena (lorlatinib) for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) whose disease has progressed on (Xalkori... Continue Reading

FDA approves lorlatinib for second- or third-line treatment of ALK-positive metastatic NSCLC (November 5, 2018)

On November 2, 2018, the Food and Drug Administration granted accelerated approval to lorlatinib (LORBRENA, Pfizer, Inc.) for patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) whose disease has progressed... Continue Reading

November Is National Lung Cancer Awareness Month (October 23, 2018)

Treatment advances – lung cancer resources and advocacy are making the difference The month of November brings lung cancer into focus. Over the past few years great strides have been made in the treatment of non-small cell lung cancer due to the... Continue Reading

Blood Test Identifies More Treatable Cancer Mutations Than Tissue Biopsy Alone (October 15, 2018)

Penn study shows patients with treatable mutations identified by liquid biopsy also largely respond to therapy October 11, 2018 PHILADELPHIA – In one of the largest clinical studies to ever examine the impact of using a blood test to detect treatable... Continue Reading

Immune-mediated Nephritis Reported to Occur with Tecentriq® (August 30, 2018)

Immune-mediated Nephritis Reported to Occur with Tecentriq® Enough patients have developed immune-mediated nephritis which has been biopsy-confirmed in many cases that the manufacturer of Tecentriq now considers this to be an important adverse reaction. ... Continue Reading

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Lung Cancer - Non-Small Cell

Prophylactic Cranial Irradiation Improves Disease-Free Survival and Brain Metastasis Rates for Locally Advanced Non-Small Cell Lung Cancer (March 20, 2019)

PHILADELPHIA, PA– Prophylactic cranial irradiation (PCI), a technique used to prevent the clinical development of brain metastases, is established as a standard approach for many patients with small cell lung cancer (SCLC) after initial therapy. While... Continue Reading

November Is National Lung Cancer Awareness Month (October 23, 2018)

Treatment advances – lung cancer resources and advocacy are making the difference The month of November brings lung cancer into focus. Over the past few years great strides have been made in the treatment of non-small cell lung cancer due to the... Continue Reading

Blood Test Identifies More Treatable Cancer Mutations Than Tissue Biopsy Alone (October 15, 2018)

Penn study shows patients with treatable mutations identified by liquid biopsy also largely respond to therapy October 11, 2018 PHILADELPHIA – In one of the largest clinical studies to ever examine the impact of using a blood test to detect treatable... Continue Reading

Overall Health, Not Just Age, is an Important Factor in Treatment of Non-Small Cell Lung Cancer (July 10, 2018)

Two clinical studies highlight the importance of evaluating overall health instead of age in the management of lung cancer. In fact, younger patients with non-small cell lung cancer (NSCLC) are more likely to receive treatment than older patients, regardless... Continue Reading

Xalkori Receives FDA Breakthrough Therapy Designation for Treatment of Lung Cancer with MET Alterations (June 5, 2018)

The U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation for Xalkori (crizotinib) for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with MET exon 14 alterations with disease progression on or... Continue Reading

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Lung Cancer - Small Cell

November Is National Lung Cancer Awareness Month (October 23, 2018)

Treatment advances – lung cancer resources and advocacy are making the difference The month of November brings lung cancer into focus. Over the past few years great strides have been made in the treatment of non-small cell lung cancer due to the... Continue Reading

Opdivo® (nivolumab) Approved for Treatment of Small Cell Lung Cancer (August 23, 2018)

The U.S. Food and Drug Administration (FDA) has approved Opdivo (nivolumab) for the treatment of metastatic small cell lung cancer (SCLC) whose cancer has progressed after platinum-based chemotherapy and at least one other line of therapy.1 About Small... Continue Reading

Precision Cancer Medicine PARP Inhibitor Promising Treatment for Small Cell Lung Cancer (June 25, 2018)

The results of a recent study published in The Journal of Clinical Oncology suggest the first new therapeutic option for Small Cell Lung Cancer (SCLC) in many years.  The study evaluated the addition of a novel precision cancer medicine called a PARP... Continue Reading

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Lymphoma

FDA approves Calquence Treatment for Treatment of Mantle Cell Lymphoma (November 6, 2017)

The U.S. Food and Drug Administration has granted accelerated approval to Calquence (acalabrutinib) for the treatment of adults with mantle cell lymphoma who have received at least one prior therapy.  Mantle cell lymphoma is a particularly aggressive... Continue Reading

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M

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Management and Prevention of Anemia Supportive Care

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Management and Prevention of Anorexia and Weight Loss Supportive Care

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Management and Prevention of Bone Complications Supportive Care

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Management and Prevention of Fatigue Supportive Care

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Management and Prevention of Mucositis Supportive Care

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Management and Prevention of Nausea and Vomiting Supportive Care

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Management and Prevention of Neutropenia Supportive Care

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Management and Prevention of Thrombocytopenia Supportive Care

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Mantle Cell Non-Hodgkin's Lymphoma

FDA Grants Approval of Calquence for the Treatment of Mantle Cell Lymphoma (May 31, 2018)

The US Food and Drug Administration (FDA) has granted approval to Calquence (acalabrutinib) for the treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Calquence is a highly-selective, potent Bruton tyrosine... Continue Reading

FDA approves Calquence Treatment for Treatment of Mantle Cell Lymphoma (November 6, 2017)

The U.S. Food and Drug Administration has granted accelerated approval to Calquence (acalabrutinib) for the treatment of adults with mantle cell lymphoma who have received at least one prior therapy.  Mantle cell lymphoma is a particularly aggressive... Continue Reading

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Melanoma

FDA Approves Keytruda for Adjuvant Treatment of Melanoma (March 4, 2019)

On February 15, 2019, the Food and Drug Administration approved pembrolizumab (KEYTRUDA®, Merck) for the adjuvant treatment of patients with melanoma with involvement of lymph node(s) following complete resection. Approval was based on EORTC1325/KEYNOTE‑054... Continue Reading

Isatuximab – Promising for Treatment of Myeloma (February 25, 2019)

A phase 3 comparative clinical trial evaluating Isatuximab has met the primary endpoint of delaying cancer progression in patients with relapsed/refractory multiple myeloma. Multiple myeloma is the second most common hematologic malignancy, with more... Continue Reading

Keytruda Approved for Treatment of Stage III Melanoma (February 21, 2019)

The U.S. Food and Drug Administration (FDA) has approved Keytruda for the adjuvant treatment of patients with melanoma with involvement of lymph node(s) following complete surgical resection. Adjuvant Therapy in Melanoma Melanoma is separated into five... Continue Reading

TVEC-Genetically Modified Virus Injection into Tumor – A Valid Treatment for Metastatic Melanoma (January 25, 2019)

Results published in the Journal of the American College of Surgeons show sustained effectiveness of disease response and favorable side effect profile. CHICAGO (January 25, 2019): Injection of a genetically modified virus that induces the body’s own... Continue Reading

Targeted Combination Treatment for Melanoma now Available (September 10, 2018)

The US Food and Drug Administration (FDA) approved the combination of Bratovi (encorafenib) and Mektovi (binimetinib)for use in patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test. About... Continue Reading

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Mesothelioma

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Metastatic Breast Cancer

FDA approves new treatment for certain advanced or metastatic breast cancers (October 5, 2017)

The U.S. Food and Drug Administration today approved Verzenio (abemaciclib) to treat adult patients who have hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer that has progressed... Continue Reading

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Metastatic Stage IV (D) Prostate Cancer

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Metastatic/Stage IVB Cervical Cancer

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Miscellaneous

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Multiple Myeloma

U.S. Food and Drug Administration Approves Empliciti® Plus Pomalidomide to Treat Certain Patients with Relapsed or Refractory Multiple Myeloma (November 12, 2018)

The U.S. Food and Drug Administration (FDA) has approved Empliciti (elotuzumab) injection for intravenous use in combination with pomalidomide and dexamethasone (EPd) for the treatment of adult patients with multiple myeloma who have received at least... Continue Reading

AbbVie and the International Myeloma Foundation Partner to Study Role of a Genetic Mutation in Multiple Myeloma (March 28, 2018)

AbbVie a research and development-based global biopharmaceutical company, and the International Myeloma Foundation (IMF) today announced they have entered into a collaboration to conduct a landmark retrospective chart review study to better understand... Continue Reading

CRISPR Enhances Cancer Immunotherapy (March 14, 2018)

Gene editing expands reach of therapeutic T cells, in mice CancerConnect News: Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient’s own immune cells —... Continue Reading

Darzalex-Effective Treatment for Smoldering Multiple Myeloma (March 7, 2018)

CancerConnect News: The use of Darzalex (daratumumab) in smoldering myeloma may be effective in delaying the time to disease progression. These results were presented at the 2017 annual meeting of the American Society of Hematology (ASH). Multiple myeloma... Continue Reading

Kyprolis Improves Survival in Recurrent Multiple Myeloma (February 8, 2018)

CancerConnect News: The addition of Kyprolis® (carfilzomib) to the standard treatment regimen, Revlimid® (lenalidomide) and dexamethasone, improves survival for patients with multiple myeloma whose disease progressed or recurred following prior therapies.... Continue Reading

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Myelodysplastic Syndrome

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N

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Neuroblastoma

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News

FDA Approves Keytruda for First-line Treatment of Head and Neck Squamous Cell Carcinoma (June 13, 2019)

FDA approves Keytruda for the first-line treatment of patients with metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC). Keytruda was approved for use in combination with platinum and fluorouracil (FU) for all patients and... Continue Reading

FDA Approves Chemoimmunotherapy Regimen for Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma (June 11, 2019)

The U.S. Food and Drug Administration granted accelerated approval to Polivy (polatuzumab vedotin-piiq), in combination with the chemotherapy Treanda (bendamustine) and Rituxan (rituximab) product (a combination known as “BR”), to treat adult... Continue Reading

Three-drug Combination Helps Curb Growth of Deadly Skin Cancer (June 10, 2019)

A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma. The approach shows promise for extending the lives of people with a type of melanoma... Continue Reading

Immunotherapy comparable to chemo for some advanced stomach cancers (June 4, 2019)

An immunotherapy drug could prove just as effective as chemotherapy in prolonging the lives of patients with advanced cancers of the stomach or food pipe. For some, the immune-boosting treatment offered improved survival compared to standard treatment. The... Continue Reading

Enzalutamide improves survival for men with metastatic hormone-sensitive prostate cancer (June 3, 2019)

After 3 years, 80% of men with metastatic hormone-sensitive prostate cancer who received enzalutamide along with testosterone suppression were alive compared to 72% of men who received standard care. Chicago – Enzalutamide, an oral androgen receptor... Continue Reading

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Non-Hodgkin's Lymphoma

FDA approves lenalidomide for follicular and marginal zone lymphoma (May 30, 2019)

On May 28, 2019, the Food and Drug Administration approved lenalidomide (REVLIMID®, Celgene Corp.) in combination with a rituximab product for previously treated follicular lymphoma (FL) and previously treated marginal zone lymphoma (MZL). The MAGNIFY... Continue Reading

Xalkori® Receives FDA Breakthrough Therapy Designation for Anaplastic Large Cell Lymphoma (July 3, 2018)

The U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation for Xalkori® (crizotinib) for the treatment of patients with relapsed or refractory systemic anaplastic large cell lymphoma (ALCL) that is anaplastic lymphoma kinase... Continue Reading

FDA Grants Approval of Calquence for the Treatment of Mantle Cell Lymphoma (May 31, 2018)

The US Food and Drug Administration (FDA) has granted approval to Calquence (acalabrutinib) for the treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Calquence is a highly-selective, potent Bruton tyrosine... Continue Reading

FDA Approves Aliqopa for Relapsed Follicular Lymphoma (May 23, 2018)

The U.S. Food and Drug Administration (FDA) granted accelerated approval to Aliqopa® (copanlisib), a novel precision cancer medicine that inhibits phosphatidylinositol 3-kinase (PI3K), for the treatment of adults with relapsed follicular lymphoma who... Continue Reading

FDA Approves Kymriah for Treatment of Relapsed or Refractory Large B-Cell Lymphoma (May 21, 2018)

On May 1, 2018, the United States Food and Drug Administration (FDA) approved Kymriah (tisagenlecleucel), a CD19-directed genetically modified autologous T-cell immunotherapy, for treatment of adult patients with relapsed or refractory diffuse large B-cell... Continue Reading

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O

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Osteosarcoma

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Other News Topics (not Types of Cancer)

FDA Approves First non-opioid Treatment for Management of Opioid Withdrawal Symptoms in Adults (May 24, 2018)

Encouraging more widespread innovation and development of safe and effective treatments for opioid use disorder remains top agency priority The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of... Continue Reading

Lutathera Pepetide Receptor Radionuclide Therapy for NETs (May 3, 2018)

CancerConnect News: Lutathera (lutetium Lu 177 dotatate) was recently approved for the treatment of neuroendocrine tumors (NETs) that typically occur in the pancreas and gastrointestinal tract. This is the first time a radioactive drug, or radiopharmaceutical,... Continue Reading

FDA and CMS Collaborate to Make Novel Cancer Biomarker Test Available (December 7, 2017)

The U.S. Food and Drug Administration (FDA) has approved the F1CDx biomarker test designed to detect mutations in 324 genes and two genomic signatures in cancer patients. In a truly collaborative effort between the FDA and The Centers for Medicare &... Continue Reading

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Ovarian Cancer

NCCN Updates Ovarian Cancer Guidelines (March 26, 2019)

The NCCN has recently updated its ovarian cancer treatment guidelines and make the following significant changes. All patients with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer should have a genetic risk evaluation and BRCA1/2... Continue Reading

About The National Ovarian Cancer Coalition (August 29, 2018)

Where do you go when you’re first delivered the news: “You have cancer”? For many women diagnosed with ovarian cancer, the answer is the National Ovarian Cancer Coalition (NOCC). With more than 80 chapters nationwide, a Web site (www.ovarian.org)... Continue Reading

Newly Diagnosed with Ovarian Cancer? 10 Must Read Tips to be an Empowered Patient (June 18, 2018)

For many years ovarian cancer has been referred to as “the silent killer” due to its vague, ignored, or misdiagnosed symp­toms. Because of this and the lack of ear­ly-detection tools, ovarian cancer often goes undiagnosed until it has reached the... Continue Reading

PARP – Checkpoint Inhibitor Combo Promising in Ovarian Cancer (May 16, 2018)

CancerConnect News: The combination of a PARP inhibitor and a checkpoint inhibitor appears promising as treatment for patients with ovarian cancer, according to results of a clinical study reported at the 2018 Society for Gynecologic Oncology Annual... Continue Reading

Rubraca® Approved as Maintenance Treatment of Recurrent Ovarian Cancer (April 9, 2018)

CancerConnect News: Rubraca® (rucaparib) has been approved for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.... Continue Reading

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P

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Pain Management Supportive Care

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Pancreatic Cancer

CD40 Combination Therapy Can Shrink Pancreatic Tumors (April 4, 2019)

A new combination of immunotherapy and chemotherapy for pancreatic cancer caused tumors to shrink in the majority of evaluable patients – 20 out of 24 as of an interim analysis of the phase 1b trial data. The early findings provide hope that this strategy... Continue Reading

Lynparza Delays Progression of BRCA-mutated Metastatic Pancreatic Cancer (March 18, 2019)

Lynparza (olaparib) improves progression-free survival (PFS) when used to treat BRCA-mutated pancreatic cancer and appears to represent a new treatment option for this hard to treat cancer. (1-4) About BRCA Mutated Pancreatic Cancer Pancreatic cancer... Continue Reading

Lynparza significantly delayed disease progression as 1st-line maintenance treatment in germline BRCA-mutated metastatic pancreatic cancer (February 28, 2019)

Results from the trial showed a significant and clinically-meaningful improvement in progression-free survival (PFS) with Lynparza (olaparib) for the treatment of BRCA-mutated pancreatic cancer. POLO is a randomised, double-blinded, placebo-controlled... Continue Reading

Laurie MacCaskill Partners with CancerConnect (October 19, 2018)

KETCHUM – LOS ANGELES: Laurie MacCaskill, a 12-year survivor of pancreatic cancer and former chair of the Pancreatic Cancer Action Network has announced a newly established partnership with Cancer Connect to support pancreatic cancer patients with information,... Continue Reading

mFOLFIRINOX Found Superior to Gemzar for Treatment Surgically Resected Pancreatic Cancer (June 19, 2018)

The results of a recently presented clinical study at the American Society of Clinical Oncology meetings last week suggest that more aggressive chemotherapy treatment improves outcomes compared to single agent Gemzar (gemcitabine) chemotherapy which has... Continue Reading

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Progressive Relapsed Hodgkin's Lymphoma

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Prostate Cancer

Enzalutamide improves survival for men with metastatic hormone-sensitive prostate cancer (June 3, 2019)

After 3 years, 80% of men with metastatic hormone-sensitive prostate cancer who received enzalutamide along with testosterone suppression were alive compared to 72% of men who received standard care. Chicago – Enzalutamide, an oral androgen receptor... Continue Reading

Calquence Improves Survival in Relapsed Chronic Lymphocytic Leukemia (May 20, 2019)

An interim analyses of the phase 3 “ASCEND” clinical trial evaluating single-agent Calquence (acalabrutinib) compared to Rituxan (rituximab) plus idelasib or bendamustine in recurrent chronic lymphocytic leukemia (CLL) is closed early due to favorable... Continue Reading

Zytig Treatment Prolongs Survival in Advanced Prostate Cancer (May 7, 2019)

Zytig (Abiraterone acetate) plus prednisone and androgen deprivation therapy (ADT) significantly extends overall survival compared with placebo plus ADT in men with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (CSPC) About... Continue Reading

Darolutamide Delays Prostate Cancer Progression in Men with Resistant Prostate Cancer (March 14, 2019)

Results of the phase III ARAMIS clinical trial were published in The New England Journal of Medicine and demonstrated that Darolutamide plus androgen deprivation therapy (ADT) significantly extends metastasis-free survival compared to placebo plus ADT... Continue Reading

Adjuvant Taxotere Doesn’t Improve Outcomes in Early Stage High Risk Prostate Cancer (February 11, 2019)

Patients with high-risk, non-metastatic prostate cancer saw no survival advantage and no delay in metastases with the addition of adjuvant docetaxel to androgen deprivation therapy (ADT), according to the results of a pivotal clinical randomized trial... Continue Reading

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Q

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R

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Radiopharmaceutical

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Rectal Cancer

Managing Side Effects From EGFR Inhibitors (April 10, 2018)

CancerConnect News: Epidermal Growth Factor Receptor (EGFR) inhibitor drugs are a type of precision cancer medicine commonly used to treat lung, colon, head and neck and other cancers that over express the EGFR.  There are several EGFR inhibitor drugs... Continue Reading

Targeting both BRAF and EGFR doubles progression-free survival in metastatic colorectal cancer (October 16, 2017)

Recent successes in genetically targeted precision cancer medicines are improving outcomes in a number of cancers.  Ensuring patients undergo genomic sequencing to determine if they have treatable targets is increasingly important to ensure patients... Continue Reading

NSAIDs Decrease Risk of Colorectal Cancer (September 18, 2017)

Nonsteroidal anti-inflammatory drugs (NSAIDS) are medicines that are used for the treatment of a wide range of musculoskeletal illnesses including spinal disorders, osteoarthritis and inflammatory conditions like rheumatoid arthritis. NSAIDs effectively... Continue Reading

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Recurrent Anal Cancer

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Recurrent Bladder Cancer

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Recurrent Breast Cancer

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Recurrent Cervical Cancer

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Recurrent Gastric Cancer

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Recurrent Liver Cancer

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Recurrent Lung Cancer - Non-Small Cell

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Recurrent Lung Cancer - Small Cell

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Recurrent Melanoma

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Recurrent Multiple Myeloma

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Recurrent Non-Hodgkin's Lymphoma

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Recurrent Ovarian Cancer

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Recurrent Pancreatic Cancer

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Recurrent Testicular Cancer

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Recurrent Uterine Cancer

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Recurrent/Relapsed Rectal Cancer

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Refactory/Recurrent Prostate Cancer

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Renal Cancer

FDA Approves Nivolumab and Ipilimumab Combination for Advanced Kidney Cancer (February 18, 2019)

The Food and Drug Administration (FDA) approved the immunotherapy drugs Opdivo and Yervoy in combination as an initial, or first-line, treatment for patients with advanced kidney cancer whose disease has an intermediate or poor prognosis. This is the... Continue Reading

Keytruda Plus Inlyta Improves Survival Compared ot Sutent for Treatment of Advanced Kidney Cancer (February 18, 2019)

Results from the randomized, phase III KEYNOTE-426 clinical trial show that first-line therapy with a combination of the PD-1 targeted immunotherapy Keytruda (pembrolizumab) and the VEGF-targeted tyrosine kinase inhibitor Inlyta (axitinib) improved overall... Continue Reading

Personalized Vaccine to be Tested in Patients with Kidney Cancer (February 13, 2019)

By pairing a novel personalized cancer vaccine with a more established immunotherapy drug that is administered to patients in an innovative fashion, scientists at Dana-Farber Cancer Institute are testing a first-of-its-kind strategy aimed at improving... Continue Reading

Personalized Vaccine to be Tested in Patients with Kidney Cancer (January 29, 2019)

By pairing a novel personalized cancer vaccine with a more established immunotherapy drug that is administered to patients in an innovative fashion, scientists at Dana-Farber Cancer Institute are testing a first-of-its-kind strategy aimed at improving... Continue Reading

Tivozanib for Renal Cell Cancer (November 16, 2018)

The precision cancer medicine tivozanib delays cancer progression and prolongs survival in individuals with advanced renal cell cancer (RCC). About tivozanib Tivozanib is an oral vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor. In... Continue Reading

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Retinoblastoma

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S

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Sarcoma

Nexavar Improves Survival for Patients with Rare Sarcomas (March 28, 2018)

Interim results from a randomized clinical trial for patients with desmoid tumors or aggressive fibromatosis (DT/DF) show that the drug Nexavar (sorafenib tosylate) extended progression-free survival compared with a placebo. Progression-free survival... Continue Reading

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Screening/Prevention Anal Cancer

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Screening/Prevention Bladder Cancer

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Screening/Prevention Breast Cancer

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Screening/Prevention Cervical Cancer

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Screening/Prevention Colon Cancer

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Screening/Prevention Esophageal Cancer

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Screening/Prevention Gastric Cancer

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Screening/Prevention Leukemia

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Screening/Prevention Liver Cancer

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Screening/Prevention Lung Cancer - Non-Small Cell

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Screening/Prevention Lung Cancer - Small Cell

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Screening/Prevention Melanoma

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Screening/Prevention Non-Hodgkin's Lymphoma

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Screening/Prevention Ovarian Cancer

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Screening/Prevention Pancreatic Cancer

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Screening/Prevention Prostate Cancer

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Screening/Prevention Rectal Cancer

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Screening/Prevention Uterine Cancer

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Skin Cancer

Three-drug Combination Helps Curb Growth of Deadly Skin Cancer (June 10, 2019)

A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma. The approach shows promise for extending the lives of people with a type of melanoma... Continue Reading

Designation for Advanced Cutaneous Squamous Cell Carcinoma (October 1, 2018)

Breakthrough Designation for Advanced Cutaneous Squamous Cell Carcinoma The U.S. Food and Drug Administration (FDA) has approved cemiplimab (REGN2810) for the treatment of adults with metastatic cutaneous squamous cell carcinoma (CSCC) and adults with... Continue Reading

May Is National Skin Cancer Detection and Prevention Month (May 18, 2018)

Sun Valley, ID —OMNI Health  (OMNI) announces the launch of skin cancer programs for national skin cancer detection and prevention month. As the month of May brings skin cancer into focus, it’s time to increase public understanding of the disease,... Continue Reading

Tafinlar® + Mekinist® Demonstrates Long Term Survival Benefit for BRAF Mutation-Positive Metastatic Melanoma (April 5, 2018)

CancerConnect News: Metastatic melanoma patients with the BRAF V600 mutation treated with the combination of Tafinlar® (dabrafenib) + Mekinist® (trametinib) can experience long term cancer free survival according to results presented at the 53rdAnnual... Continue Reading

PD-1 Antibody Cemiplimab Appears Promising for Treatment of Squamous Cell Carcinoma of the Skin (February 2, 2018)

Cemiplimab an investigational human antibody targeting PD-1 (programmed cell death protein 1), is yet another “checkpoint inhibitor” that was evaluated in 82 patients with advanced cutaneous squamous cell carcinoma (CSCC).  Early trial results suggest... Continue Reading

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Skin Cancer Overview

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Soft Tissue Sarcomas

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Stage I Cervical Cancer

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Stage I Node Negative Breast Cancer

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Stage I Ovarian Cancer

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Stage I-II Testicular Cancer

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Stage I/Smoldering Myeloma Multiple Myeloma

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Stage II-IV Ovarian Cancer

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Stage III Bladder Cancer

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Stage III Melanoma

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Stage III Testicular Cancer

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Stage IV (D)/Relapsed Colon Cancer

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Stage IV Anal Cancer

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Stage IV Liver Cancer

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Stage IV Melanoma

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Stage IV Pancreatic Cancer

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Stage IV Rectal Cancer

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Stage IV Uterine Cancer

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Stage IV/Metastatic Bladder Cancer

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Stage IV/Recurrent Esophageal Cancer

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Stages 0-I Bladder Cancer

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Stages I-II Anal Cancer

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Stages I-II Gastric Cancer

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Stages I-II Melanoma

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Stages I-III Esophageal Cancer

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Stages I-III Liver Cancer

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Stages I-III Pancreatic Cancer

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Stages I-III Rectal Cancer

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Stages I-III Uterine Cancer

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Stages I-IIIA Lung Cancer - Non-Small Cell

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Stages II-III Bladder Cancer

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Stages II-III Breast Cancer

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Stages II-III Multiple Myeloma

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Stages II-IVA Cervical Cancer

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Stages III-IV Gastric Cancer

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Stages IIIB-IV Lung Cancer - Non-Small Cell

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Stem Cell Transplant

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Supportive

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Supportive Care

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Supportive Care Breast Cancer

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T

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T-Cell Non-Hodgkin's Lymphoma

Mogamulizumab Superior to Vorinostat in Cutaneous T Cell Lymphoma (December 13, 2017)

Results were recently presented at the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta from a international comparative clinical trail evaluating mogamulizumab in patients with previously treated cutaneous T-cell lymphoma... Continue Reading

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Testicular Cancer

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Throat Cancer

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Thyroid Cancer

Loxo-292 Promising for Lung and Other “RET Fusion” Cancers (June 4, 2018)

On Saturday, Loxo Oncology in a presentation at the American Society of Clinical Oncology annual meeting in Chicago unveiled clinical trial data for LOXO-292, a novel precision cancer medicine targeting tumors containing a mutated protein known as RET. About... Continue Reading

Lower Thyroid Stimulating Hormone Levels Elevate Risk of Thyroid Cancer (September 20, 2017)

There is an increased risk of thyroid cancer associated with lower-than-normal thyroid hormone levels, a finding that could have a major impact on patients fighting the disease. The Yale-led study, published in American Association for Cancer Research... Continue Reading

Pass it On: It’s National Thyroid Awareness Month (September 8, 2017)

The thyroid gland is a butterfly-shaped organ that is below the Adam’s apple in the front part of the neck. It produces, stores, and releases hormones that regulate vital body functions. Thyroid cancer happens when cells in the thyroid grow out of control.... Continue Reading

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Types of Cancer

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U

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Uncategorized

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Uterine Cancer

GARNET Study Suggets Dostarlimab Promising for Uterine/Endometrial Cancer (March 28, 2019)

An early phase clinical trial evaluating dostarlimab in women with recurrent or advanced endometrial cancer appears promising.  These data were presented at the 2019 Society for Gynecologic Oncology (SGO) Annual Meeting on Women’s Cancer in Honolulu,... Continue Reading

Precision Cancer Treatment with Afinitor Encouraging in Uterine Cancer (April 4, 2018)

CancerConnect News: Combination therapy with Afinitor (everolimus) and Femara (letrozole) demonstrated encouraging activity in the treatment of advanced endometrial cancer, according to a report from the Society of Gynecologic Oncologists meeting this... Continue Reading

Uterine Cancer: The Next Immunotherapy Frontier? (January 30, 2018)

CancerConnect News: All gynecologic cancers are challenging to treat. They can be hard to find and are usually diagnosed when they are advanced. Although these cancers can be held at bay with surgery or chemotherapy, they often return and become difficult... Continue Reading

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V

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Vaginal Cancer

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Video

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W

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X

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Y

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Z

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